A look at today's 49ers game vs. Seattle, including: broadcast information, three keys to the game, matchup to watch and injury report.
49ERS GAME AT A GLANCE
Opponent: at Seattle
Time: 5:30 p.m.
Line: Seahawks by 3
Records: 49ers 1-0, Seattle 1-0
TV/radio: Ch. 3 (Al Michaels play-by-play, Cris Collinsworth color), 810, 1320
MATCHUP TO WATCH
49ers wide receiver Anquan Boldin vs. cornerback Richard Sherman
Boldin had plenty of room to roam last week against a Packers secondary that fielded two inexperienced safeties and mostly used zone coverage. The Seahawks, meanwhile, have one of the most talented secondaries in the NFL and love to use press coverage. That's especially true of former Stanford star Sherman, one of the tallest and most physical cornerbacks in the league. Look for plenty of contact and plenty of jawing between two of the feistiest players at their positions.
THREE KEYS TO GAME
Ex-Cal standout Marshawn Lynch has surpassed 100 rushing yards three straight times against the 49ers. Like San Francisco, the Seahawks had trouble establishing the run in Week 1 but will try to get on track in Week 2. The battle between 49ers nose tackle Ian Williams and Seahawks center Max Unger should be compelling.
Both teams will try to contain the opposing quarterback on the ground. Russell Wilson proved especially slippery to the 49ers in December, holding onto the ball for 19 seconds on one play as defenders flailed at his feet.
If the Seahawks play a lot of man-to-man coverage, it could open up running room for Colin Kaepernick. He had 22 yards on the ground against a Packers defense committed to stopping the run but one ill-equipped to handle the 49ers' passing game.
Questionable: RB LaMichael James (knee)
Out: DT Jordan Hill (biceps)
Doubtful: CB Brandon Browner (hamstring), SS Jeron Johnson (hamstring)
Questionable: DE Chris Clemons (knee)
Probable: DE Cliff Avril (hamstring), T Michael Bowie (shoulder), DT Tony McDaniel (groin), DT Brandon Mebane (ankle), WR Sidney Rice (knee), TE Luke Willson (oblique)