SANTA CLARA Vernon Davis said he's waiting for team doctors to give him the go-ahead to play Sunday, which would be the first game he's played against his younger brother, Colts cornerback Vontae Davis.
Vernon Davis, who suffered a strained left hamstring late in Sunday's loss to Seattle, was the only 49er who did not practice Friday, though the tight end said he was able to run on a side field while the rest of the team practiced. He is listed as questionable on the team's injury report.
"I'm feeling pretty good; sore, bruised up, but that comes with the business, comes with the game," he said. "Definitely, my focus is on this game. ... We shall see when Sunday comes."
Davis said he was surprised the injury occurred since he spends so much time before and after practice stretching his hamstrings, groins and calves.
"That's all I do," he said. "When you guys don't see me, I'm in here stretching."
If Davis can't play, backups Vance McDonald and Garrett Celek would step in. It also might lead to Chris Harper's debut. Acquired just before the season began, Harper is listed as a receiver but is studying how to play the tight-end role Delanie Walker had the last two seasons. Harper was inactive the first two games.
Vontae Davis, meanwhile, was a first-round pick by the Dolphins in 2009. He was traded to Indianapolis last year.
Alex Smith delivering Looking very much like the 49ers of 2011, Alex Smith and the Chiefs beat the Eagles 26-16 on Thursday in Philadelphia. The win improved Kansas City's record to 3-0 and increased the likelihood the 49ers will get better-than-expected compensation in the next draft.
The 49ers already received a second-round pick in the trade that sent Smith to the Chiefs earlier this year. The 49ers parlayed that pick into defensive end Tank Carradine.
They also get a pick in the 2014 draft, which as of now is a third-round selection but improves to a second-rounder if the Chiefs finish .500 or better.
Injuries Defensive end Ray McDonald practiced for the first time this week and expects to play against the Colts.
McDonald, Davis, running back LaMichael James (knee) and safety Eric Reid (concussion) are listed as questionable. Reid also is on track to play but must pass one final step in the league's post-concussion protocol.
Linebackers NaVorro Bowman (wrist) and Aldon Smith (back), guard Mike Iupati (shoulder), quarterback Colin Kaepernick (foot) and defensive tackle Justin Smith (shoulder) are listed as probable.