Jean Segura hit a three-run homer, and the Milwaukee Brewers broke out of an offensive slumber at home to support Kyle Lohse in a 5-2 win over the San Diego Padres on Wednesday night.

The Rangers lost a run on a replay review Wednesday.

Baseball players operate on a funny clock during the sixth-month marathon of a season.

The Ricketts family celebrated a big victory Wednesday night at the Cubs' charity function, only a few hours after marking the 100th anniversary of Wrigley Field with a trademark-worthy loss.

Alfredo Simon pitched into the seventh inning despite erratic control, Jay Bruce drove in a run for a fifth consecutive game and the Cincinnati Reds beat the Pittsburgh Pirates 5-2 Wednesday night.

Nelson Cruz batted in five runners with a grand slam and a solo home run to lift the Baltimore Orioles to a 10-8 victory over the Toronto Blue Jays in the second installment of a three-game set.

Adam LaRoche's tiebreaking RBI single off the first pitch from Fernando Salas capped a four-run rally in the bottom of the ninth inning, and the Washington Nationals came back to beat the Los Angeles Angels 5-4 Wednesday night to avoid a sweep.

With a 360-foot relay in the ninth inning, the New York Mets prevented a hard-fought victory from vanishing in the wind.

Yankees pitcher Michael Pineda was ejected for using pine tar less than two weeks after appearing to get away with using a foreign substance in another game against Boston, and the Red Sox beat New York 5-1 on Wednesday night.

Chris Tillman allowed season-highs in hits, home runs and earned runs against the Blue Jays. None of that bothered Baltimore manager Buck Showalter.

Jason Kipnis drove in Nick Swisher with a two-out double in the seventh inning, sending the Cleveland Indians to a 5-3 win over the Kansas City Royals on Wednesday night.

On the night he became the franchise's career leader in total bases, Paul Konerko liked what he saw from some of the younger Chicago White Sox.

ALLENTOWN, Pa. - The Philadelphia Phillies believe they have a long-term solution at third base, a revolving-door position filled mostly by players from outside their farm system ever since Scott Rolen ascended to baseball heaven - that's St. Louis in case you've forgotten - in the middle of the 2002 season.

Bruce Chen repeats the refrain as he walks through the Kansas City Royals' clubhouse, his professional home now for six seasons, his longest tenure in a big-league career that stretches back to 1998.

Michael Pineda was ejected for using pine tar less than two weeks after appearing to get away with using a foreign substance in another game against Boston, and the Red Sox beat the New York Yankees 5-1 Wednesday night.

Albert Pujols was so wired - and so busy talking and texting friends around baseball - after hitting his 500th career home run Tuesday night that the Los Angeles Angels slugger didn't get to sleep until about 4 a.m. and managed only three or four hours of sleep, at best.

The Chicago Cubs marked Wrigley Field's 100th birthday in dramatic fashion Wednesday, allowing the Arizona Diamondbacks to rally for five runs in the ninth inning and a 7-5 victory.

Josh Fields knew he wasn't as sharp as the previous two nights, when he saved games against the Mariners.

In the hours after Albert Pujols hit his 500th career homer, his cellphone kept buzzing early into Wednesday morning.

Jeff Samardzija supplied the answer Wednesday in a quick, terse tone before the question was finished.

On the 100th anniversary of the first game at Wrigley Field, the team with the worst record in the major leagues won.

This time, Michael Pineda couldn't get away with using a foreign substance.

Less than two weeks after pitching against Boston with what appeared to be pine tar on his pitching hand, the New York Yankees' Michael Pineda was ejected from a game against the Red Sox on Wednesday night after umpires found a foreign substance on his neck.

Arizona Diamondbacks outfielder Mark Trumbo has a stress fracture in his left foot.

Over the course of a 162-game season, every team will go through some rough stretches.

Tampa Bay Rays manager Joe Maddon has an interesting suggestion after Yunel Escobar's stuck out a pitch with a 4-2 count: give him credit for a walk.

Arizona Diamondbacks outfielder Mark Trumbo will be sidelined for an extended period of time because of a stress fracture in his left foot.

San Diego Padres starter Josh Johnson is scheduled to undergo elbow ligament-replacement surgery for the second time and will miss the entire season.

With one swing, Kyle Seager hopes he ended his personal skid at the plate and the Seattle Mariners' slide.

San Diego Padres pitcher Josh Johnson will undergo Tommy John surgery Thursday after a recent exam revealed damage to the ulnar collateral ligament in his right elbow.

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