Buffalo Bills running back LeSean McCoy (25) beats San Francisco 49ers defenders for a touchdown during the second half of an NFL football game Sunday, Oct. 16, 2016, in Orchard Park, N.Y. McCoy ran for 140 yards and three scores in the Bills’ 45-16 victory.
Buffalo Bills running back LeSean McCoy (25) beats San Francisco 49ers defenders for a touchdown during the second half of an NFL football game Sunday, Oct. 16, 2016, in Orchard Park, N.Y. McCoy ran for 140 yards and three scores in the Bills’ 45-16 victory. Bill Wippert The Associated Press
Buffalo Bills running back LeSean McCoy (25) beats San Francisco 49ers defenders for a touchdown during the second half of an NFL football game Sunday, Oct. 16, 2016, in Orchard Park, N.Y. McCoy ran for 140 yards and three scores in the Bills’ 45-16 victory. Bill Wippert The Associated Press
49ers with Matt Barrows

49ers with Matt Barrows

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Numbers favor hosts in 49ers’ loss to Bills in Buffalo

October 16, 2016 11:06 PM