Buffalo Bills running back LeSean McCoy (25) beats San Francisco 49ers defenders for a touchdown during the second half of an NFL football game Sunday, Oct. 16, 2016, in Orchard Park, N.Y. McCoy ran for 140 yards and three scores in the Bills’ 45-16 victory.
Buffalo Bills running back LeSean McCoy (25) beats San Francisco 49ers defenders for a touchdown during the second half of an NFL football game Sunday, Oct. 16, 2016, in Orchard Park, N.Y. McCoy ran for 140 yards and three scores in the Bills’ 45-16 victory. Bill Wippert The Associated Press
Buffalo Bills running back LeSean McCoy (25) beats San Francisco 49ers defenders for a touchdown during the second half of an NFL football game Sunday, Oct. 16, 2016, in Orchard Park, N.Y. McCoy ran for 140 yards and three scores in the Bills’ 45-16 victory. Bill Wippert The Associated Press
On the 49ers

On the 49ers

The latest Niners news with Chris Biderman

Numbers favor hosts in 49ers’ loss to Bills in Buffalo

October 16, 2016 11:06 PM