SANTA CLARA -- Anquan Boldin was limited in practice for the second straight day with a hamstring injury and is listed as questionable to play Thursday against the Seahawks.
Colin Kaepernick's favorite target hasn't missed a start due to injury since the end of the 2011 when he was with the Ravens. Also listed as questionable are running back Carlos Hyde (foot) and right tackle Erik Pears (back).
Hyde was questionable before Sunday's game but ended up taking 21 carries. Pears, meanwhile, will be matched against Seattle's Cliff Avril who is Pro Football Focus' top-rated 4-3 defensive end through six weeks.
Running back Reggie Bush (calf) and receiver Bruce Ellington (calf), both of whom missed Sunday's game, are listed as probable to play. Bush's presence could take some of the workload off of Hyde Thursday.
For Seattle, notable defenders like safety Kam Chancellor (shoulder), cornerback Richard Sherman (ankle) and linebacker Bobby Wagner (pectoral) are probable to play.
Questionable: WR Anquan Boldin (hamstring), RB Carlos Hyde (foot), T Erik Pears (back)
Probable: G Alex Boone (shoulder), LB Navorro Bowman (shoulder), LB Ahmad Brooks (shoulder), RB Reggie Bush (calf), TE Vernon Davis (knee), WR Bruce Ellington (calf), TE Vance McDonald (chest), S Eric Reid (chest), T Joe Staley (knee), G Brandon Thomas (ankle)
Out: CB Marcus Burley (hand), RB Derrick Coleman (concussion), DT Jordan Hill (quadricep), C Patrick Lewis (ankle), LB Nick Moody (ankle)
Questionable: DE Demarcus Dobbs (shoulder)
Probable: DE Cliff Avril (ankle), G Justin Britt (hip), S Kam Chancellor (shoulder), DE Frank Clark (hamstring), T Garry Gilliam (ankle), WR Tyler Lockett (hip), RB Marshawn Lynch (hamstring), CB Richard Sherman (ankle), CB Tye Smith (hip), LB Bobby Wagner (pectoral)